Survival Arts

I didn't forget the American Community Survey protestors

During the time between I allowed my blog to go down, and the time I restored it, Google's crawlers did the understandably necessary thing, and culled the dead links from others' sites to mine. Not a big deal to me, but if there's any one reason to leave this site up, it's to service those engaged in public discussion of the unconstitutional outrage of the American Community Survey (ACS). About four years ago, I posted a short note commenting on Texas congressman Ron Paul's criticism of the survey entitled "None of Your Business!': the American Community Survey" which has become the very most heavily posted item here.

Folks, apologies once again for having let the site go down.

Nothing sinister, just didn't pay attention

Apologies for letting the site go down: my hosting service didn't pick up on a change of bank I made when I moved to Manhattan for school. I've been very, very busy, and what little blog-like activity I've engaged in since the fall has been on Facebook. Yep, as a college student, I find Facebook very useful... who'd a thunk it?

Test Driven Development in Python: A Quick-start Approach

In my copious spare time these last few weeks, I gave a Tech Talk to some local users' groups in Google's Ann Arbor office, "Test Driven Development in Python: A Quick-start Approach". I was deeply impressed at the quality of technical folk I met there, some of whom had actually written some of the programming frameworks I use at Google. I took some pics of the audience from the speaker's POV, my first use of an iPhone for such an application.

Winston Tsang was kind enough to have taken some of his own photos of the event; I particularly like this one:

Christopher Hitchens speaks at Google in Mountain View, California

As a Googler, I have the most incredible perks, not the least of which is a level of participation in "corporate civics" that I've never enjoyed elsewhere. Among those perks is the privilege of nominating authors to speak at Google in a sponsored venue. One of my nominations, public intellectual Christopher Hitchens, spoke at our Mountain View campus about a week before my departure to New York City:

ABSTRACT

Author Christopher Hitchens discusses his book "God Is Not Great: How Religion Poisons Everything" as a part of the Authors@Google series. The author of Why Orwell Matters and Letters to a Young Contrarian, Christopher Hitchens is a Vanity Fair contributing editor, a Slate columnist, and a regular contributor to The Atlantic Monthly. He has also written for The Nation, Granta, Harper's, The Washington Post, and is a frequent television and radio guest. Born in England, Hitchens was educated at Balliol College, Oxford, where he received a degree in philosophy, politics, and economics. He now lives in Washington, D.C., and he became a U.S. citizen in 2007. This event took place on August 16, 2007 at Google headquarters in Mountain View, CA.

WILT: taking cancer seriously enough to really cure it

Eight weeks ago, I hosted Dr. Aubrey de Grey for his second talk at Google in Mountain View, California, a follow-up to his earlier Google talk in the SENS series, "WILT: taking cancer seriously enough to really cure it":

ABSTRACT

The intrinsic genetic instability of cancer cells makes age-related cancers harder to ... all » postpone or treat than any other aspect of aging. Any therapy that a cancer can resist by activating or inactivating specific genes is unlikely to succeed long-term, because pre-existing cancer cells with the necessary gene expression pattern will withstand the therapy and proliferate. WILT (Whole-body Interdiction of Lengthening of Telomeres) seeks to pre-empt this problem by deleting from as many of our cells as possible the genes needed for telomere elongation. Cancers lacking these genes can never reach a life-threatening stage by altering gene expression, only by acquiring new genes, which is far more unlikely. Continuously-renewing tissues can be maintained by periodic reseeding with telomere elongation-incompetent stem cells that have had their telomeres lengthened in vitro with exogenous telomerase. I will describe why WILT may become a uniquely comprehensive anti-cancer modality, and the practicalities of performing it and avoiding side-effects.

Everything You Wanted To Know About Stem Cells... But Were Afraid To Ask

Some weeks back, my (now) friend Dr. Daniel Kraft, a physician scientist at Stanford, came to Google at my invitation to give a talk, "Everything You Wanted To Know About Stem Cells... But Were Afraid To Ask":

ABSTRACT

Stem cell technology and the debate surrounding it has generated a great deal of excitement ... all » and controversy in recent years. The field is surrounded by misconceptions, hype and yet very significant potential. In this talk we'll cover: defining what are stem cells really and where do they come from... the differences between embryonic stem cells and 'adult stem cells' (i.e. derived from our own bone marrow, fat, umbilical cord blood, placentas and even our kids teeth) and emerging technologies to utilize these cells in powerful and novel ways. We'll cover current clinical uses of stem cells, ongoing clinical trials in regenerative medicine (i.e. using marrow derived cells to treat heart attacks, vascular disease, stroke and even diabetes), upcoming trials utilizing embryonic stem cells, and some of the likely near term and future applications as well as challenges remaining in order for this field to reach its full potential.

OK, time to prairie dog

Time to pop my head back up into the blogosphere. I've got a few moments to mention what many of my friends have known for a while: I've moved to New York City for school, as an undergraduate (junior) transfer student in biochemistry at Columbia University, pre-med. These last few months have been among the busiest of my life to date... scratch that, these have indeed been the busiest.

I bit the bullet and did the Facebook thing: it was damned near useless to me before, now it's indispensable. Having spent far too much time there, I'm turning my attention back here. More later, stay tuned...

Aubrey de Grey: "Prospects for extending healthy life - a lot"

Aubrey de Grey gave a Tech Talk at Google's Mountain View campus this week, and I was privileged to attend. I've seen him give a longer, earlier version of this presentation before - at Stanford in June 2005 - and was impressed more than ever. Enjoy:

ABSTRACT

It may seem premature to be discussing approaches to the effective elimination of human ... all » aging as a cause of death at a time when essentially no progress has yet been made in even postponing it. However, two aspects of human aging combine to undermine this assessment. The first is that aging is happening to us throughout our lives but only results in appreciable functional decline after four or more decades of life: this shows that we can postpone the functional decline caused by aging arbitrarily well without knowing how to prevent aging completely, but instead by increasingly thorough molecular and cellular repair. The second is that the typical rate of refinement of dramatic technological breakthroughs is rather reliable (so long as public enthusiasm for them is abundant) and is fast enough to change such technologies (be they in medicine, transport, or computing) almost beyond recognition within a natural human lifespan. In this talk I will explain, first, why (presuming adequate funding for the initial preclinical work) therapies that can add 30 healthy years to the remaining lifespan of healthy 55-year-olds may arrive within the next few decades, and, second, why those who benefit from those therapies will very probably continue to benefit from progressively improved therapies indefinitely and thus avoid debilitation or death from age-related causes at any age.

Telomolecular Nanotechnologies

What a day! Just as I'm getting ready to attend Aubrey de Grey's talk at Google, I find out that a martial arts training buddy of mine, Dr. Pete Lohstroh, recently left his research position at UC Davis to take a senior scientist position at Telomolecular Nanotechnologies, specializing in the application of nanocircles to telomere extension therapy (one of several approaches they're taking). Congratulations Pete!

"Nanomedicine opens the way for nerve cell regeneration"

Nanomedicine opens the way for nerve cell regeneration

"The ability to regenerate nerve cells in the body could reduce the effects of trauma and disease in a dramatic way. In two presentations at the NSTI Nanotech 2007 Conference, researchers describe the use of nanotechnology to enhance the regeneration of nerve cells. In the first method, developed at the University of Miami, researchers show how magnetic nanoparticles (MNPs) may be used to create mechanical tension that stimulates the growth and elongation of axons of the central nervous system neurons. The second method from the University of California, Berkeley uses aligned nanofibers containing one or more growth factors to provide a bioactive matrix where nerve cells can regrow..."

Nanoparticles Delivery of 'Suicide DNA' Kills Prostate Tumors

Nanoparticles Delivery of 'Suicide DNA' Kills Prostate Tumors

"...using nanoparticles developed by members of the Alliance for Nanotechnology in Cancer, a team of investigators at the Lankenau Institute for Medical Research, in Philadelphia, has developed a DNA-based therapeutic agent that has the potential to treat both enlarged prostates and localized prostate tumors. When tested in mice, this new agent specifically targeted prostate tissue, producing no toxic effects in surrounding tissues..."